Isaac Clarke has gone through hell, been broken, and almost dies on several occasions. He lost his girlfriend, Nicole, and destroyed the Red Marker that was mined off of the USG Ishimura. He wakes up two years later after being in a coma, and finds himself in the same situation on a space station known as the Sprawl. He goes through betrayal, and also delusions of his dead girlfriend that is a manifest of the Marker. He escaped, thanks to Ellie Langford, and soon settles down on one of the colonies orbiting around Saturn, expecting to get away from his past and live a quiet life. Yet he was still dragged into the Marker epidemic, and ended up learning the truth about the Markers, as well as destroying the Moon. And he expected to die and rest in peace, knowing that he gave Earth a tomorrow. But the universe apparently had other plans for him. Isaac wakes to find himself on a unknown planet, which was currently a wasteland, and he also appeared to be in a body of a pony. Many questions running through his mind as he stumbles into the new world, and fights for survival as he did so many times before. Will he ever get home? Will he find a safe haven instead? Or will he possibly meet ponies who could be friendly?